THC does indeed "open" the third eye, through its effects on D2 which deactivate the pineal gland (take note of the somewhat confusing terminology here; open = deactivated, closed = activated). The pineal gland's job is to produce melatonin, which inhibits REM and REM-like states (which are generally required for legitimate spiritual experiences, like the ones psychedelics can provide). Through increasing the effect of dopamine and other agonists at D2, THC increases the activity of photosensitive ganglion cells in the retina which are normally activated by melanopsin, a photopigment, which in turn lowers the activity of the pineal gland and suppresses melatonin production, thus allowing for these REM-like states to emerge. However, the downside is that high levels of acetylcholine also seem to at least preferred, if not required, for these truly spiritual experiences. Cholinergic drugs drastically increase such effects in psychedelics, and the 5-HT2A receptor, which classical psychedelics activate, increases the release of acetylcholine. Cannabinoids, like THC, on the other hand, have actions directly opposite to those of acetylcholine, and will cause concentrations of it to drop. So in other words, the reason it feels like it "opens" the pineal gland is because it does, however it also lowers your ability to achieve the more astral experiences; basically, it puts you in that pineal mood but doesn't give you the full experience. This is largely why THC feels psychedelic, but isn't exactly the same.
I hope that helps.
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