I find that it's impossible to ignore a state of mindfulness with psilocin in my system, and meditation becomes a much more interactive experience for me. Eyes open, eyes closed, being confrontational with the phenomena around you, one seems to get a realistic grasp on the chemistry going on. It's just a good way to get a real feeling for the beauty of things such as impermanence, taking the best of things to carry into the next moment, and just thinking about how everything around you is in a special place just like you.