hey! great thread, i have a few experiences on the topic
When I went to central america, I was prescribed 2 pills of chloroquine once a week to prevent malaria. This caused me to wild quite quickly with and without vibrations but every time I got lucid I would wake up. Also I'd have twisted nightmares about my fears. one night I dreamt I was lying in bed in the dark watching my roommates bed and 2 hooded dark figures first aproach her, them to me and just as I become lucid I wake up.
that was frustrating the nightmares as well as the waking up in the middle of the night from becoming lucid haha.
I also take sleeping pills to sleep on occasion, i only take 1/2 or a full one, and these ones happened to be xanax, since I was in CA, I had long lucid dreams with those-mind you when I do lucid dream now, most of the time my lucids' are long as I stretch them out. then I dont remember half of it cause im lazy with the note-taking 
Also DXM is found in cough syrup and when I was younger like 7 years ago I took it to try n achieve an OBE, I was new to lucid then, so as soon as i got the vibrations I FREAKED out and didnt try it again. It sort of tranquilizes you like ketamine does (which is gross)
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