Most of the drugs they use in hospitals will not help you with this. Furthermore, the drugs that they use that DO help you with this will often be used in doses high enough to just make you black out (i.e., anesthetize you). That means no dreams, no OBEs, just blank, and then you wake up in the recovery room. There are exceptions, but they are rare. More than likely if you get a full OBE from anesthesia then you're in some sort of physical or mental trauma, in which case you could be having one anyway and really won't be concerned with astral explorations. Opiates/opioids and GABAergics (which make up most of the anesthetics used on humans) will not cause OBEs. If anything, they can cause a mild delirium which, particularly with opioids, can cause a few dream-like sequences to occur, but they'll be more like hypnagogia than anything. They will also not cause these effects in a hospital setting.
The drugs you're looking for are dissociative anesthetics, NMDA receptor antagonists. The most common one of these used on humans is nitrous oxide, and I hear xenon is becoming popular. The further away you get from those, the less likely you are to find a hospital that uses one of these drugs on people. They are, however, frequently used as recreational drugs (including nitrous oxide) because they can be euphoric and do legitimately provide OBEs at high doses. However, these OBEs will differ somewhat from traditional methods, but they are OBEs. I'm pretty sure they work through the same mechanisms in the brain. Examples of these drugs would be DXM, ketamine, and PCP, among many lesser-known chemicals.
Though they can provide OBEs, they really shouldn't be thought of as a replacement for normal methods of leaving your body. They're more like a separate experience entirely, and that goes for each individual drug.
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